આ MCQ મોડ્યુલ આના પર આધારિત છે: Mechanism Volumes
Mechanism Volumes
આ મૂલ્યાંકન આના પર આધારિત હશે: Mechanism Volumes
મૂલ્યાંકન બનાવવામાં તેમની સામગ્રી સામેલ કરવા ચિત્રો, PDF અથવા Word દસ્તાવેજ અપલોડ કરો.
Mechanism of Breathing, Respiratory Volumes and Capacities
Part 1 ended with a puzzle built into the anatomy: the lung has no muscle of its own, so it cannot inflate itself. This part shows how the body solves that — by changing the volume of the air-tight box the lung sits in, and letting pressure do the rest.
14.2 Mechanism of Breathing
The movement of air into and out of the lungs is carried out by creating a pressure gradient between the lungs and the atmosphere.
• Inspiration can occur if the pressure within the lungs (intra-pulmonary pressure) is less than the atmospheric pressure — i.e., there is a negative pressure in the lungs with respect to atmospheric pressure.
• Expiration takes place when the intra-pulmonary pressure is higher than the atmospheric pressure.
The diaphragm and a specialised set of muscles — external and internal intercostals between the ribs — help in the generation of such gradients.
Inspiration, step by step
- Inspiration is initiated by the contraction of the diaphragm, which increases the volume of the thoracic chamber in the antero-posterior axis.
- The contraction of the external intercostal muscles lifts up the ribs and the sternum, causing an increase in the volume of the thoracic chamber in the dorso-ventral axis.
- The overall increase in the thoracic volume causes a similar increase in pulmonary volume.
- An increase in pulmonary volume decreases the intra-pulmonary pressure to less than the atmospheric pressure, which forces the air from outside to move into the lungs — i.e., inspiration.
Expiration, step by step
- Relaxation of the diaphragm and the intercostal muscles returns the diaphragm and sternum to their normal positions, and reduces the thoracic volume and thereby the pulmonary volume.
- This leads to an increase in intra-pulmonary pressure to slightly above the atmospheric pressure, causing the expulsion of air from the lungs — i.e., expiration.
We have the ability to increase the strength of inspiration and expiration with the help of additional muscles in the abdomen. On an average, a healthy human breathes 12–16 times per minute.
| Feature | Inspiration | Expiration |
|---|---|---|
| Muscle state | Diaphragm and external intercostals contract | Diaphragm and intercostals relax |
| Diaphragm shape | Flattens — increases volume along the antero-posterior axis | Returns to its dome shape |
| Ribs and sternum | Lifted up — increases volume along the dorso-ventral axis | Return to normal positions |
| Thoracic and pulmonary volume | Increases | Decreases |
| Intra-pulmonary pressure | Less than atmospheric (negative) | Slightly above atmospheric |
| Air movement | Into the lungs | Out of the lungs |
| Nature | Active — requires muscular contraction | Passive at rest — relaxation and recoil |
What to do. Take a transparent plastic bottle and cut off its base. Push a Y-shaped glass or plastic tube through a rubber stopper and fix two small balloons to the two arms of the Y; these are the lungs. Seal the stopper into the bottle's mouth so the bottle is air-tight. Now stretch a large rubber sheet across the open base and tie it firmly — this is the diaphragm. Pull the rubber sheet downward, then release it, and watch the balloons.
Observations. Pulling the rubber sheet down inflates both balloons; releasing it lets them deflate. The balloons were never squeezed or blown into — nothing touched them at all.
What the model shows. Exactly the real mechanism. Pulling the sheet down mimics contraction of the diaphragm, which increases the volume of the thoracic chamber. The overall increase in thoracic volume causes a similar increase in pulmonary volume, which decreases the intra-pulmonary pressure to less than the atmospheric pressure, and this forces the air from outside to move into the lungs. Releasing the sheet mimics relaxation, which reduces the volume and raises the pressure slightly above atmospheric, causing the expulsion of air.
What the model gets right that a diagram cannot. It makes vivid the point that we cannot directly alter the pulmonary volume — the balloons are inflated only through the sealed chamber around them.
The hole in the side. The balloons now fail to inflate, however hard you pull the sheet, because the chamber is no longer air-tight: air rushes in through the hole instead of down the tube, and no pressure difference develops across the balloon wall. This is precisely what happens in a real punctured chest, and it is why the chapter stresses that the thoracic chamber is anatomically an air-tight chamber.
One limitation to note honestly. The model represents only the diaphragm. The real chest also expands through the external intercostals lifting the ribs and sternum along the dorso-ventral axis, which a rigid bottle cannot imitate.
14.2.1 Respiratory Volumes and Capacities
By adding up a few respiratory volumes, one can derive various pulmonary capacities, which can be used in clinical diagnosis. Learn the four volumes first; every capacity is then just a sum of them.
The four volumes
The five capacities
| Capacity | Definition | Composition |
|---|---|---|
| Inspiratory Capacity (IC) | Total volume of air a person can inspire after a normal expiration | TV + IRV |
| Expiratory Capacity (EC) | Total volume of air a person can expire after a normal inspiration | TV + ERV |
| Functional Residual Capacity (FRC) | Volume of air that will remain in the lungs after a normal expiration | ERV + RV |
| Vital Capacity (VC) | The maximum volume of air a person can breathe in after a forced expiration, or equivalently the maximum volume that can be breathed out after a forced inspiration | ERV + TV + IRV |
| Total Lung Capacity (TLC) | Total volume of air accommodated in the lungs at the end of a forced inspiration | RV + ERV + TV + IRV, i.e. vital capacity + residual volume |
🎯 Interactive: Volume or capacity? Look it up
Value / composition: Approximately 500 mL
Volume of air inspired or expired during a normal respiration. At 12 to 16 breaths per minute, a healthy man can inspire or expire approximately 6000 to 8000 mL of air per minute.
🎯 Competency-Based Questions
Q1. Calculate IC, EC, FRC, VC and TLC for the healthy adult. L3 Apply
EC = TV + ERV = 500 + 1100 = 1600 mL.
FRC = ERV + RV = 1100 + 1200 = 2300 mL.
VC = ERV + TV + IRV = 1100 + 500 + 2800 = 4400 mL.
TLC = RV + ERV + TV + IRV = 1200 + 4400 = 5600 mL, which is also VC + RV.
Q2. In the smoker, TLC is normal but VC is reduced and RV raised. Explain why these three findings are consistent with each other. L4 Analyse
Q3. Fill in the blanks: Inspiration occurs when intra-pulmonary pressure is ______ atmospheric pressure. It is initiated by contraction of the ______, which increases thoracic volume in the ______ axis, while the ______ intercostals lift the ribs and sternum, increasing volume in the ______ axis. L1 Remember
Q4. Why can a spirometer not measure residual volume, and which two capacities does this make unmeasurable by spirometry alone? L4 Analyse
Q5. “Expiration is just inspiration in reverse.” Evaluate. L5 Evaluate
(i) One is active, the other is not. Inspiration is initiated by the contraction of the diaphragm and of the external intercostal muscles — muscular work. Expiration at rest is produced by relaxation of the diaphragm and the intercostal muscles, which returns the diaphragm and sternum to their normal positions. Relaxation is not the opposite muscular act; it is the absence of one, with elastic recoil doing the work.
(ii) The pressure changes differ in size. Inspiration needs the intra-pulmonary pressure less than atmospheric; expiration needs it only slightly above atmospheric. The chapter's wording “slightly” is deliberate.
(iii) Different muscles serve the forced versions. We have the ability to increase the strength of inspiration and expiration with the help of additional muscles in the abdomen, and forced expiration additionally recruits the internal intercostals — muscles that play no part in quiet breathing at all.
(iv) The volumes are not mirror images. IRV is 2500–3000 mL but ERV only 1000–1100 mL, and RV can never be expelled at all — so the lung's capacity to take in far exceeds its capacity to push out.
The accurate statement: expiration reverses the direction of air flow, but it is a passive elastic return rather than an active mirror of inspiration.
🧠 Assertion–Reason Questions
For each pair choose: (A) Both A and R are true and R is the correct explanation of A. (B) Both A and R are true but R is not the correct explanation of A. (C) A is true but R is false. (D) A is false but R is true.
Assertion (A): Air moves into the lungs during inspiration.
Reason (R): An increase in pulmonary volume decreases the intra-pulmonary pressure to less than atmospheric pressure.
Assertion (A): Total lung capacity is always greater than vital capacity.
Reason (R): Total lung capacity includes the residual volume, which is the air remaining in the lungs even after a forcible expiration.
Assertion (A): Contraction of the diaphragm increases the volume of the thoracic chamber in the dorso-ventral axis.
Reason (R): The diaphragm forms the lower side of the thoracic chamber and is dome-shaped.